Send Inquiry

Request To Call Back

Koselugo 10mg Capsule

Name: Koselugo 10mg Capsule
Brand: K. K. PHARMA SOLUTIONS
Price: 400000.0 INR
Availability: InStock

Price 400000.0 INR/ Unit

Get a Price/Quote

MOQ : 1 Unit

Koselugo 10mg Capsule Specification

Pacakaging (Quantity Per Box)
28 capsules per box

Origin of Medicine
Imported

Dosage Form
Solid oral dosage form

Life Span
36 months from manufacture date

Salt Composition
Selumetinib 10mg

Indication
Treatment of symptomatic, inoperable plexiform neurofibromas in NF1

Packaging Type
Blister Strips

Brand Name
Koselugo

Drug Type
Allopathic

Ingredients
Selumetinib

Physical Form
Capsule

Function
Targeted therapy for NF1-related plexiform neurofibromas

Recommended For
Adults and children with neurofibromatosis type 1 (NF1)

Dosage
As directed by a physician

Dosage Guidelines
Take exactly as prescribed, on an empty stomach

Suitable For
Adults and pediatric patients

Quantity
Variable (as per pack)

Storage Instructions
Store below 30C in a dry place, protect from light

Patient Information Leaflet
Included in pack

Special Precautions
Monitor cardiac and ocular function during therapy

Approval Status
US FDA approved for NF1 in pediatric patients aged 2 years and older

Prescription/Non Prescription
Prescription

Color
Light blue and white

Market Authorization Country
Multiple international markets including US, EU, India

Side Effects
May include diarrhea, nausea, rash, increased blood creatine phosphokinase, vomiting, abdominal pain

Interactions
Potential interaction with strong CYP3A4 inhibitors/inducers

Route of Administration
Oral

Contraindications
Hypersensitivity to Selumetinib or any inactive ingredient

Shape
Hard gelatin capsule

Regulatory Approval
FDA, EMA, CDSCO (India) approved

ATC Code
L01EE04

Koselugo 10mg Capsule About

Koselugo 10mg Capsule is used to treat children aged 2 years and older with neurofibromatosis type 1 (NF1), a genetic condition that causes the growth of tumors on nerve tissues. It works by targeting a protein involved in tumor growth. It helps slow the growth of tumors and provides relief from the symptoms.

How Koselugo Works for NF1

Koselugo 10mg functions by targeting the MEK pathway, which is involved in the growth of plexiform neurofibromas associated with neurofibromatosis type 1 (NF1). By inhibiting this pathway, Koselugo helps reduce the size and symptoms of inoperable plexiform neurofibromas, improving quality of life for both adults and children affected by this condition.

Usage Guidelines and Administration

Koselugo is taken orally, exactly as prescribed by your physician, and should be consumed on an empty stomach. The capsule form makes it convenient for both pediatric and adult patients. Dosage is determined by your healthcare provider based on individual needs, and strict adherence to the recommended schedule is crucial for optimal results.

Important Precautions and Monitoring

Regular monitoring of cardiac and ocular function is necessary during Koselugo therapy, as directed by your healthcare provider. Always inform your doctor about other medications, as Koselugo may interact with strong CYP3A4 inhibitors or inducers. Do not take Koselugo if you have known hypersensitivity to selumetinib or any of its inactive ingredients.

FAQ's of Koselugo 10mg Capsule:

Q: How should I take Koselugo 10mg capsules for NF1?

A: Koselugo should be taken orally, exactly as prescribed by your healthcare provider, typically on an empty stomach. Swallow the hard gelatin capsule whole with a glass of water; do not crush or chew. Adhere to the dosing schedule set by your physician for best results.

Q: What are the potential benefits of using Koselugo in patients with NF1?

A: Koselugo is designed to target and reduce the size and symptoms of inoperable plexiform neurofibromas associated with NF1. It greatly improves symptom management, which may enhance physical function and overall quality of life in both pediatric and adult patients.

Q: When should Koselugo not be used?

A: Koselugo should not be used if you have a known hypersensitivity to selumetinib or any other ingredient in the capsule. If you experience any allergic reactions or have a history of such sensitivities, inform your doctor immediately.

Q: What side effects might occur with Koselugo therapy?

A: Common side effects include diarrhea, nausea, rash, increased blood creatine phosphokinase, vomiting, and abdominal pain. If you notice any severe or persistent side effects, contact your healthcare provider promptly.

Q: Where is Koselugo available, and how is it supplied?

A: Koselugo is approved and supplied in multiple international markets, including the US, EU, and India, and is usually available in blister strips containing 28 capsules per box. It is prescription-only and should be obtained from authorized pharmacies.

Q: What precautions should I follow while on Koselugo treatment?

A: Regular monitoring of your heart and eyes is essential during treatment. Inform your physician about any other medications you take due to potential interactions with CYP3A4 inhibitors or inducers. Always store Koselugo capsules below 30C, in a dry place away from light.

Tell us about your requirement