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Simulect Injection

Name: Simulect Injection
Brand: K. K. PHARMA SOLUTIONS
Price: 76300.0 INR
Availability: InStock

Price 76300.0 INR/ Piece

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MOQ : 10 Parcels

Simulect Injection Specification

Packaging Type
Vial

Life Span
Check expiry date on the pack

Origin of Medicine
Switzerland

Salt Composition
Basiliximab 20 mg

Dosage Form
Injection

Pacakaging (Quantity Per Box)
1 vial per box

Brand Name
Simulect

Indication
Preventing acute rejection in kidney transplant

Drug Type
Biological

Ingredients
Basiliximab

Physical Form
Liquid

Function
Immunosuppressant

Recommended For
For prevention of acute organ rejection in renal transplant patients

Dosage
As prescribed by physician

Dosage Guidelines
Administered intravenously. Follow physician guidance.

Suitable For
Adults and paediatric patients (age 1-17 years) receiving a kidney transplant

Quantity
20 mg/5 ml per vial

Storage Instructions
Store at 2-8C. Do not freeze.

Appearance
Clear, colourless to slightly yellow solution

Contraindications
Known hypersensitivity to basiliximab or other mouse-derived proteins

ATC Code
L04AA10

Administration Route
Intravenous infusion

Regulatory Approval
US FDA and EMA approved

Special Precautions
Monitor for hypersensitivity and infection risk

Patient Population
Renal transplant recipients

Prescription Required
Yes

Shelf life (unopened)
2 years from manufacturing date

Reconstitution Needed
No, ready to use

Simulect Injection Trade Information

Minimum Order Quantity
10 Parcels

Supply Ability
500 Parcels Per Month

Delivery Time
7 Days

About Simulect Injection

Simulect Injection belongs to the immunosuppressant group of medicines. It regulates the immune system to prevent rejection of the kidney transplantation. It is usually prescribed in combination with some other medicines.

Simulect Injection is a prescription medicine that must be administered by a healthcare professional. You must receive the exact dose of it as per the prescription. An overdose of this medicine may have serious side effects on the body.

The common side effects of this medicine are nausea, vomiting, constipation, etc. It may also cause an injection site reaction (redness, pain, and swelling). The medicine can safely be used in children.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you some laboratory tests to know the effects of the medicine in the body.

Mechanism of Action

Simulect (basiliximab) is a biological immunosuppressant that works by inhibiting the activation of lymphocytes, a type of white blood cell involved in organ rejection. By binding to a specific receptor on these cells, it prevents the immune response that can cause the body to reject a transplanted kidney.

Administration and Dosage

Simulect is given by intravenous infusion as prescribed by your physician, usually around the time of transplantation. Each vial contains 20 mg/5 ml and is ready to use without reconstitution. The dose and schedule may vary depending on the patient's age and clinical condition. Only a healthcare professional should administer Simulect.

Storage and Shelf Life

Store Simulect at 2-8C and do not freeze. The product remains stable for up to two years from the manufacturing date, provided it is kept unopened and proper storage guidelines are followed. Always check the expiry date before use to ensure safety and efficacy.

Safety and Precautions

While Simulect can be highly effective in preventing kidney transplant rejection, it requires medical supervision due to potential risks such as hypersensitivity reactions and increased susceptibility to infection. It is contraindicated for patients with known allergies to basiliximab or mouse-derived proteins.

FAQ's of Simulect Injection:

Q: How is Simulect Injection administered to patients?

A: Simulect is administered as an intravenous infusion, usually in a hospital setting and under the supervision of a healthcare professional. The doctor will determine the appropriate dosage and timing for each patient, often around the time of the kidney transplant procedure.

Q: What is the primary benefit of using Simulect Injection?

A: The main benefit of Simulect is its ability to significantly reduce the risk of acute organ rejection following a kidney transplant. By weakening certain aspects of the immune response, it helps the body accept the new organ and improves transplant success rates.

Q: Who can receive Simulect Injection?

A: Simulect is recommended for both adult and pediatric patients (ages 1-17 years) who are undergoing kidney transplantation. It should not be used in individuals with known hypersensitivity to basiliximab or mouse-derived proteins.

Q: What precautions should be taken during the use of Simulect?

A: Patients receiving Simulect should be closely monitored for signs of hypersensitivity or allergic reactions as well as infection. Administration is performed in a healthcare setting so immediate treatment can be given if adverse effects occur.

Q: When should Simulect Injection not be used?

A: Simulect should not be used in anyone with a known allergy to basiliximab or proteins derived from mice. Inform your healthcare provider if you have any history of such allergies before starting treatment.

Q: Where should Simulect Injection be stored before use?

A: Simulect should be stored in a refrigerator at a temperature between 2C and 8C. Do not freeze the injection and always keep it in its original packaging until use to protect it from light and contamination.

Q: What is the process for receiving Simulect during a kidney transplant?

A: The process involves preparing a single-dose vial before administration, with Simulect infused intravenously on or around the day of the kidney transplant. A repeat dose may be given as prescribed. Healthcare professionals will monitor you closely throughout the process.

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